A Type 1 diabetic with out insulin, Nicolette "Nicki" Clark was last seen leaving her Lake Hopatcong house on Oct. 31, family members said on Facebook.
Her boyfriend Joe Dobie, 28, is also missing and was last seen on Tuxedo Parkway in Newark, Nicki's family said.
The couple took off in a silver Chevrolet tracker with a soft, leather top, license plate V26KTL.
The Clarks were not available for comment when Daily Voice reached out Saturday evening.
Click here on how to contact the Clark family.
Click here to follow Daily Voice Wyckoff-Franklin Lakes and receive free news updates.